Rader DNA Project

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DNA and Genealogy by Jim Rader

American Society of Human Genetics Publishes Updated Genetic Ancestry Testing Statement

Posted: 14 May 2010 03:05 AM PDT From: The Genetic Genealogist

Today at noon, the American Society of Human Genetics lifted an embargo on “Inferring Genetic Ancestry: Opportunities, Challenges, and Implications (pdf),” which will be published in the May 14th issue of the American Journal of Human Genetics.

This paper is a follow-up to a 2008 paper called the “ASHG Ancestry Testing Statement and Recommendations” in which a committee from the ASHG addressed concerns about the claims made by genetic ancestry testing companies. I wrote an article here on the blog at the time – The ASHG Ancestry Testing Statement and Recommendations – that highlighted a number of concerns I had about the statement and the recommendations.

When I wrote the November 13, 2008 blog post, I began by pointing out my personal positions, which have largely remained unchanged in the intervening 1.5 years:

After years of experience in this field, I am a proponent of genetic genealogy testing, a scientific endeavor that has been utilized by more than 800,000 customers.
I believe that education, not more government regulation, is the most efficient and appropriate answer to the issues raised by the authors of the paper.
I believe that autosomal genetic genealogy testing is in its infancy and should only be used with the understanding that the results are only extremely rough estimates that are subject to change as the field develops.

magazine October 2006 Issue Adventures in Genetic Genealogy links
What can you really learn about your family history from a few cheek cells? We sent a professional genealogist on a quest to discover the truth behind the developing science of DNA. By Maureen A. Taylor

"African American Lives" www.pbs.org/wnet/aalives
Sorenson Molecular Genealogy Foundation www.smgf.org
Oxford Ancestors www.oxfordancestors.com
Genetealogy www.genetealogy.com
DNA Print Genomics dnaprint.com
Relative Genetics www.relativegenetics.com
Family Tree DNA www.familytreedna.com
Chromosomal Laboratories www.chromosomallabs.com
DNA Heritage www.dnaheritage.com
International Society of Genetic Genealogy www.isogg.org
MitoSearch www.mitosearch.org
Sorenson Molecular Genealogy Foundation www.smgf.org
YBase www.ybase.org
YHRD www.yhrd.org
YMatch www.relativegenetics.com
YSearch www.ysearch.org

When FTDNA first launched, they had 300 samples,

2001 they tested 1,700 samples, 2002 they tested 4,800 samples, 2004 they had tested over 34,000.

When the National Geographic Project first met with them, they estimated that they might be doing up to 20,000 samples per year. As things got closer, they were estimating 100,000 samples per year. Since they started receiving samples in May, they have processed over 64,000 samples up through October 2005.

10/3/2006: Family Tree DNA hits new milestones solidifying its leadership with the largest DNA databases in the field of Genetic Genealogy with 112,139 records:

www.familytreedna.com

HISTORY UNEARTHED DAILY

www.familytreedna.com

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The Adam Roder line has this Y Chromosome (In Greene County Tn Solomon Lutheran church Rader families

Kit	Name		*	3	3	1	3	3	3	4	3	4	3	3	3	4	4	4	4	4	4	4	4	4	4	4	4	4	4	G	Y	Y	4	6	5	5	C	C	4	4
			H	9	9	9	9	8	8	2	8	3	8	9	8	5	5	5	5	5	4	3	4	4	6	6	6	6	6	A	C	C	5	0	7	7	D	D	4	3
			a	3	0		1	5	5	6	8	9	9	2	9	8	9	9	5	4	7	7	8	9	4	4	4	4	0	T	A	A	6	7	6	0	Y	Y	2	8
			p					a	b				\|		\|		a	b							a	b	c	d		A	II	II
			l										1		2															H4	a	b					a	b
			balkins
5377	Dr. William Rader	reference	I	15	23	15	10	15	15	11	13	11	14	12	31	17	8	9	11	11	25	14	19	29	14	15	15	16	12	11	20	21	14	15	19	18	32	34	12	10
17292	Freddie Norman Rader	24/25 related	I	15	23	15	10	15	15	11	13	11	14	12	30	17	8	9	11	11	25	14	19	29	14	15	15	16
13270	William Yale Reeder	'35/37 related	I yugosol	15	23	15	10	15	15	11	13	11	14	12	31	18	8	9	11	11	25	14	19	29	14	15	15	16	12	10	20	21	14	15	19	18	32	34	12	10

The Casper Rotter line this Y Chromosome (In Greene County Tn Timber Ridge church Rader families

5185	James Lee Rader	reference	R1b	13	24	14	11	11	14	12	12	12	13	13	29	17	9	9	11	11	25	15	19	30	15	15	17	18	11	11	19	23	16	15	16	17	34	37	13	12
6589	Earl Francis Rader	37/37 Very tightly related	R1b	13	24	14	11	11	14	12	12	12	13	13	29	17	9	9	11	11	25	15	19	30	15	15	17	18	11	11	19	23	16	15	16	17	34	37	13	12

Come and Join us ! click here to order http://www.familytreedna.com/surname_det.asp?group=Rader

FTDNATiP™: When clicking on "FTDNATiP™" you will be given the statistical probabilities of when a common ancestor between James Lee Rader and that person may have lived.

Interpreting Genetic Distance within Surname Projects 37 Markers

Distance	Relatedness	Explanation
0	Very Tightly Related	37/37 Your perfect match means you share a common male ancestor with a person who shares your surname (or variant). Your relatedness is extremely close with the common ancestor predicted, 50% of the time, in 5 generations or less and with a 90% probability within 16 generations. Very few people achieve this close level of a match. All confidence levels are well within the time frame that surnames were adopted in Western Europe.
1	Tightly Related	36/37 You share the same surname (or a variant) with another male and you mismatch by only one 'point' at only one marker--a 36/37 match. It's most likely that you matched 24/25 or 25/25 on a previous Y-DNA test and your mismatch will be found within DYS 576, 570, CDYa or CDYb. Very few people achieve this close level of a match. Your mismatch is within the range of most well established surname lineages in Western Europe.
2	Related	35/37 You share the same surname (or a variant) with another male and you mismatch by only two 'points' --a 35/37 match. It's most likely that you matched 24/25 or 25/25 on previous Y-DNA tests and your mismatch will be found within DYS 439 or DYS 385 A, 385 B,389-1 and 389-2, from our first panel of 12 markers, or from within the second panel at DYS #'s 458, 459 a, 459b, 449, or within 464 a-d. If you matched exactly on previous tests you probably have a mismatch at DYS 576, 570, CDYa or CDYb in our newest panel of markers. Your mismatch is likely within the range of most well established surname lineages in Western Europe.
3	Related	34/37 You share the same surname (or a variant) with another male and you mismatch by three 'points' --a 34/37 match. Because of the volatility within some of the markers this is slightly tighter then being 11/12 or 23/25 and it's most likely that you matched 24/25 or 25/25 on previous Y-DNA tests. Your mismatch will most often be found within DYS 439 or DYS 385 A, 385 B,389-1 and 389-2 from our first panel of 12 markers, or within the second panel: DYS #'s 458, 459 a, 459b, 449, or within 464 a-d. If you matched exactly on previous tests you probably have a mismatch at DYS 576, 570, CDYa or CDYb in our newest panel of markers. Your mismatch is likely within the range of most well established surname lineages in Western Europe.
4	Probably Related	33/37 You share the same surname (or a variant) with another male and you mismatch by four 'points' --a 33/37 match. Because of the volatility within some of the markers this is about the same as being 11/12 and it's most likely that you matched 23/25 or 24/25 on previous Y-DNA tests. If you matched exactly on previous tests you probably have a mismatch at DYS 576, 570, CDYa or CDYb in our newest panel of markers. If several or many generations have passed it is likely that these two lines are related through other family members. That would require that each line had passed a mutation and one person would have experienced at least 2 mutations. The only way to confirm is to test additional family lines and find where the mutations took place. Only by testing additional family members can you find the person in between each of you...this 'in betweener' becomes essential for you to find, and without him the possibility of a match exists, but further evidence must be pursued. If you test additional individuals you will most likely find that their DNA falls in-between the persons who are 4 apart demonstrating relatedness within this family cluster or haplotype.
5	Only Possibly Related	32/37 You share the same surname (or a variant) with another male and you mismatch by five 'points' --a 32/37 match. It is most likely that you did not 12/12 or 24/25 or 25/25 in previous Y-DNA tests. If several or many generations have passed it is possible that these two group members are related through other family members. That would require that each line had experienced separate mutations and one person would have experienced at least 2 mutations. The only way to confirm or deny is to test additional family lines and find where the mutation took place. Only by testing additional family members can you find the person in between each of you...this 'in betweener' becomes essential for you to find, and without him only the possibility of a match exists, further evidence should be pursued. If you test additional individuals you must find the person whose DNA results falls in-between the persons that are 5 apart demonstrating relatedness within this family cluster or haplotype.

Interpreting Genetic Distance --- 25 Markers

Distance	Relatedness	Explanation
0	Related	Your perfect 25/25 match means you share a common male ancestor with a person who shares your surname (or variant). These two facts demonstrate your relatedness.
1	Related	You share the same surname (or a variant) with another male and you mismatch by only one 'point' on only one marker. For most closely related and same surnamed individuals, the mismatch markers are usually either DYS 439 or DYS 385 A, 385 B,389-1 and 389-2 from our first panel of 12 markers, and on the following from the second panel: DYS #'s 458 459 a 459b 449, 464 a-d, which have shown themselves to move most rapidly. The probability of a close relationship is very high.
2	Probably Related	You share the same surname (or a variant) with another male and you mismatch by two 'point' on on from the 25 markers we tested. For most closely related and same surnamed individuals, the mismatch markers are usually either DYS 439 or DYS 385 A, 385 B,389-1 and 389-2 from our first panel of 12 markers, and on the following from the second panel: DYS #'s 458 459 a 459b 449, 464 a-d, which have shown themselves to move most rapidly. The probability of a close relationship is good, however your results show mutations, and therefore more time between you and the other same surnamed person.
3	Probably Not Related	You share the same surname (or a variant) but are off by 3 'points' or 3 locations on the 25 markers tested. If enough time has passed it is possible that you and another distantly related family members' line each have had a mutation, or perhaps 2. The only way to prove that is to test additional family lines and find where the mutation took place. Expressed another way, assume your score puts you at 3 on the clock. Assume the person 3 from you is at the 9 position. Only by further testing can you find the person in between each of you...this in 'betweener' becomes essential for you to find, and in their absence the possibility of a match exists, but further evidence should be pursued.

Ysearch, the largest worldwide public Y-DNA database with the most extensive number of markers exceeds 17,000 records (haplotypes) and 170,000 ancestors names. http://www.ysearch.org/

The Genographic Project is a real time effort to map how humankind populated the earth. It is a five-year research partnership between National Geographic and IBM with support from the Waitt Family Foundation, and public participation through Family Tree DNA. The three main pillars of the project include:
Global field science: The core of the project is the collection DNA samples from indigenous populations, which contains key genetic markers that have remained relatively unaltered over hundreds of generations making them reliable indicators of ancient migratory patterns. Dr. Wells and a group of 10 scientists from prominent international institutions will conduct the field and laboratory research. One additional research center will focus on analyzing DNA from ancient remains. The Waitt Family Foundation is funding this component of the Genographic Project. An international advisory board will oversee the selection of indigenous populations for testing as well as adherence to strict sampling and research protocols.
Public participation and Awareness Campaign: The general public can take part in the project by purchasing a Genographic Project Public Participation Kit and submitting their own cheek swab sample, allowing them to track the overall progress of the project as well as learn their own migratory history. These personal results are stored anonymously to protect the privacy of participants. National Geographic will regularly update the public and the scientific community on project findings, including through the website and through National Geographic's many other media platforms worldwide.
Genographic Legacy Project: Proceeds from the sale of the Genographic Public Participation Kits help fund future field research and a legacy project, which will build on National Geographic's 117-year-long focus on world cultures. The legacy project will support education and cultural preservation projects among participating indigenous groups.

BYU Center for Molecular Genealogy have been moved from the BYU campus in Provo, Utah, to the Sorenson Molecular Genealogy Foundation facility in Salt Lake City, Utah. www.smgf.org Although the intent and goals of the Molecular Genealogy Research Project remain unchanged, the operations associated with the collection and analysis of DNA samples and genealogical records will be conducted by the Foundation who will be the primary sponsor of the project. We anticipate the project to progress with greater efficiency as a result of consolidating all personnel and resources into a single location.

They would like to have a complete biological pedigree chart with names, places and dates of birth. Ideally, we would like to receive a GEDCOM file with up to 8 generations of ancestry (beginning with the donor as generation number one). However, anyone that can submit a minimum of four complete generations on paper or disk can participate. we encourage participants to submit as many generations as they have, on paper or on a diskette as a GEDCOM file. Individuals that have already participated in the MGRP database and would like to add more genealogical information to the one they submitted at the time of the DNA collection can do so by sending it to:

The Sorenson Molecular Genealogy Foundation 2511 South West Temple Salt Lake City, UT 84115
Please indicate the name of the participant and the place where the sample was submitted.

<mailto:info@smgf.org> Genealogy Foundation, or by calling (801) 461-9783. Please, contact us to discuss the possibility of collecting samples internationally.

the Rader DNA Project